April 7th, 2011: penny stocks with daily loss of over 20% with $20,000+ in trading volume on OTC market tier
| Symbol | Company Name | Last | Net Change | % Chg | $ Volume | Volume |
| SINX | SIONIX | 0.1361 | -0.0507 | -27.14% | $3,162,909 | 19154234 |
| ALIF | ARTIFICIAL LIFE | 0.485 | -0.175 | -26.52% | $1,099,906 | 2177725 |
| GSDC | GOLDSANDS DEVELOPMENT | 0.27 | -0.11 | -28.95% | $695,710 | 2147381 |
| BARZ | 5 BARZ INTL | 1.12 | -0.36 | -24.32% | $545,288 | 443125 |
| CUBV | CUBA BEVERAGE CO | 0.115 | -0.1172 | -50.47% | $544,229 | 5126212 |
| BMOD | BIOMODA | 0.055 | -0.017 | -23.61% | $172,120 | 2829880 |
| DGIN | DIVERSITY GRO INTL | 0.06 | -0.02 | -25.00% | $135,988 | 1865690 |
| PSTX | PATIENT SAFETY TECHS | 1.07 | -0.28 | -20.74% | $105,862 | 95375 |
| CGFIA | COLORADO GOLDFIELDS | 0.0007 | -0.0002 | -22.22% | $71,943 | 92906350 |
| SGTI | SHENGTAI PHARMACEUTICALS | 2.045 | -0.555 | -21.35% | $68,952 | 33500 |
| VSHC | VISUAL HEALTH CARE CORP | 0.008 | -0.0037 | -31.62% | $56,600 | 5927698 |
| ISCR | INSTACARE | 0.04 | -0.01 | -20.00% | $41,972 | 1067423 |
| PGIE | PGI ENERGY | 0.0093 | -0.0032 | -25.60% | $41,406 | 3726189 |
| BLLN | BRILLIANT TECHNOLOGIES | 0.01 | -0.003 | -23.08% | $37,541 | 3338400 |
| REMD | REMODEL AUCTION INC COMMON | 0.0004 | -0.0001 | -20.00% | $36,761 | 97365113 |
| VMSYQ | VISUAL MGMT SYSTEMS | 0.0051 | -0.0027 | -34.62% | $33,140 | 5206941 |
| EVDR | EVADER CORP | 0.0069 | -0.0021 | -23.33% | $23,742 | 2902857 |