OTC stock market penny stocks with daily loss of over 20% on $20,000+ in trading volume for April 19th, 2011
| Symbol | Company Name | Last | Net Change | % Chg | $ Volume | Volume |
| MDFI | MEDEFILE INTL | 0.0057 | -0.0041 | -41.84% | $8,552,808 | 771281892 |
| ADPAS | ADELPHIA RECOVERY TRUST | 0.0074 | -0.0078 | -51.32% | $3,192,089 | 440288310 |
| KNKT | KUNEKT CORP | 0.77 | -0.24 | -23.76% | $762,940 | 911504 |
| EAHC | EXPLORE ANYWHERE HOLDING CORP | 0.23 | -0.1 | -30.30% | $503,596 | 2054470 |
| MSLP | MUSCLEPHARM CORP | 0.0605 | -0.0157 | -20.60% | $412,884 | 6806945 |
| BITKF | BIOSIGN TECHNOLOGIES | 0.8087 | -0.4721 | -36.86% | $387,833 | 460500 |
| BIEL | BIOELECTRONICS CORP | 0.0059 | -0.0031 | -34.44% | $286,250 | 65779224 |
| BRZL | BRAZOS INTL EXPLORATION | 0.004 | -0.0017 | -29.82% | $249,654 | 61346701 |
| ADSV | ALLIED SECURITY INNOVATIONS INC | 0.0027 | -0.0013 | -32.50% | $182,223 | 58789925 |
| AEMD | AETHLON MEDICAL | 0.102 | -0.0313 | -23.48% | $158,125 | 1460601 |
| BLUG | BLUGRASS ENERGY | 0.014 | -0.0058 | -29.29% | $140,907 | 8653626 |
| TNEN | TRUE NORTH ENERGY CORP | 0.11 | -0.05 | -31.25% | $99,590 | 978414 |
| EARH | EARTH DRAGON RES INC | 0.0353 | -0.0297 | -45.69% | $96,986 | 2157813 |
| NGMC | NEXT GENERATION ENERGY | 0.58 | -0.31 | -34.83% | $85,395 | 122729 |
| VSYS | VISCOUNT SYSTEMS | 0.2 | -0.37 | -64.91% | $73,885 | 397167 |
| HFGB | HUIFENG BIO-PHARMA TECH | 0.185 | -0.094 | -33.69% | $59,816 | 270550 |
| MBRTF | MBMI RESOURCES INC | 0.06 | -0.0961 | -61.56% | $40,814 | 504500 |
| XNEZ | XNE | 0.013 | -0.017 | -56.67% | $38,675 | 2975000 |
| RNTL | ROCKWOOD NATIONAL CO | 0.027 | -0.018 | -40.00% | $24,627 | 750175 |
| VYTR | VYTERIS | 0.16 | -0.04 | -20.00% | $24,051 | 145216 |
| VIZS | VIZSTAR | 0.031 | -0.009 | -22.50% | $24,015 | 765310 |
| NEGS | NX GLOBAL | 0.0008 | -0.0002 | -20.00% | $22,549 | 27178238 |