12.21.2010
| Symbol | Company Name | Last | Net Change | % Chg | $ Volume | Volume |
| ACTC | ADVANCED CELL TECH | 0.263 | 0.0342 | 14.95% | $22,274,480 | 87067832 |
| ASRG | AMERICAN SURGICAL HOLDINGS | 2.78 | 1.46 | 110.61% | $2,912,658 | 1055574 |
| SPAG | SPARTAN GOLD LTD COMMON | 0.5 | 0.091 | 22.25% | $2,390,406 | 5026382 |
| ECTE | ECHO THERAPEUTICS | 1.55 | 0.35 | 29.17% | $1,806,440 | 1187746 |
| OPTZ | OPTIMIZED TRANS | 0.0014 | 0.0002 | 16.67% | $380,966 | 175441335 |
| TDCP | 3 DICON | 0.015 | 0.0025 | 20.00% | $326,415 | 20214659 |
| IMGG | IMAGING 3 INC | 0.1699 | 0.0174 | 11.41% | $295,226 | 1824725 |
| HYTM | HYTHIAM | 0.11 | 0.03 | 37.50% | $221,767 | 2137817 |
| GNTA | GENTA INC COMMON | 0.034 | 0.0038 | 12.58% | $218,377 | 6396028 |
| ZVTK | ZEVOTEK | 0.006 | 0.0019 | 46.34% | $179,644 | 29943021 |
| LBYE | LIBERTY ENERGY | 0.6 | 0.1 | 20.00% | $158,412 | 274249 |
| CRCUF | CANARC RESOURCE | 0.2307 | 0.0393 | 20.53% | $136,319 | 608531 |
| KDKN | KODIAK ENERGY | 0.33 | 0.03 | 10.00% | $116,198 | 358711 |
| CMIN | CONSTITUTION MINING CORP | 0.204 | 0.039 | 23.64% | $96,844 | 517238 |
| PMXO | PMX COMMUNITIES | 0.62 | 0.17 | 37.78% | $86,070 | 140378 |
| IMEK | IMETRIK M2M SOLUTIONS | 0.46 | 0.06 | 15.00% | $81,850 | 180000 |
| HOMS | HOMELAND SECURITY CAPITAL | 0.02 | 0.008 | 66.67% | $73,859 | 2651983 |
| SDRG | SILVER DRAGON RESOURCES | 0.11 | 0.025 | 29.41% | $68,811 | 691675 |
| CAMH | CAMBRIDGE HEART | 0.225 | 0.036 | 19.05% | $64,781 | 312489 |
| ANTS | ANTS SOFTWARE | 0.3449 | 0.0449 | 14.97% | $56,134 | 174253 |
| VCTZF | VALCENT PRODUCTS INC | 0.225 | 0.025 | 12.50% | $43,242 | 191865 |
| AVOI | ADVANCED VOICE RCGNTN | 0.15 | 0.05 | 50.00% | $39,524 | 276505 |
| ACUZW | ACCURIDE CORP | 0.2 | 0.06 | 42.86% | $33,014 | 189046 |
| RMCP | REVOLUTIONS MEDICAL | 0.5 | 0.06 | 13.64% | $32,141 | 72531 |
| BBLU | BLUE EARTH | 1.64 | 0.23 | 16.31% | $27,406 | 18100 |
| HUTC | HUGHES TELEMATICS | 2.74 | 0.29 | 11.84% | $27,146 | 10100 |
| PWEB | PACIFIC WEBWORKS | 0.08 | 0.01 | 14.29% | $25,734 | 308000 |
| ECOB | ECOBLU PRODUCTS | 0.0638 | 0.0072 | 12.72% | $25,549 | 434400 |
| MGLT | MAGNOLIA SOLAR CORP | 0.5 | 0.05 | 11.11% | $24,123 | 49480 |
| PNTV | PLAYERS NETWORK | 0.18 | 0.025 | 16.13% | $21,253 | 134846 |